Integrated Multiomics Analyses of the Molecular Landscape of Sarcopenia in Alcohol‐Related Liver Disease

Integrated Multiomics Analyses of the Molecular Landscape of Sarcopenia in Alcohol‐Related Liver Disease

ABSTRACT Background Skeletal muscle is a major target for ethanol‐induced perturbations, leading to sarcopenia in alcohol‐related liver disease (ALD). The complex interactions and pathways involved in adaptive and maladaptive responses to ethanol in skeletal muscle are not well understood. Unlike hy...

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Main Authors: Nicole Welch, Pugazhendhi Kannan, Saurabh Mishra, Annette Bellar, Vandana Agrawal, Grahame Kidd, Emily Benson, Ryan Musich, Raya Tabbalat, Ling Li, J. Mark Brown, Belinda Willard, Karyn A. Esser, Laura E. Nagy, Srinivasan Dasarathy
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
alcohol‐related liver disease
hypoxia‐inducible factor‐1‐alpha
mitochondrial oxidative dysfunction
protein acetylation
redox ratio
sarcopenia
Online Access:https://doi.org/10.1002/jcsm.13818
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https://doi.org/10.1002/jcsm.13818

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