Five-Year Incidence and Progression of Diabetic Retinopathy in Patients with Type II Diabetes in a Tertiary Care Center in Lebanon
Objective. To estimate the 5-year incidence of progression rate and regression rate and risk factors for diabetic retinopathy (DR) in a cohort of Lebanese patients with type II diabetes. Methods. We followed a cohort of 462 Lebanese patients with type II diabetes for over 5 years at the American Uni...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2017/9805145 |
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| author | Carl-Joe Mehanna Maamoun Abdul Fattah Hani Tamim Mona P. Nasrallah Raya Zreik Sandra S. Haddad Jaafar El-Annan Randa S. Haddad Haytham I. S. Salti |
| author_facet | Carl-Joe Mehanna Maamoun Abdul Fattah Hani Tamim Mona P. Nasrallah Raya Zreik Sandra S. Haddad Jaafar El-Annan Randa S. Haddad Haytham I. S. Salti |
| author_sort | Carl-Joe Mehanna |
| collection | DOAJ |
| description | Objective. To estimate the 5-year incidence of progression rate and regression rate and risk factors for diabetic retinopathy (DR) in a cohort of Lebanese patients with type II diabetes. Methods. We followed a cohort of 462 Lebanese patients with type II diabetes for over 5 years at the American University of Beirut Medical Center. Patients underwent yearly complete ophthalmic evaluation and fundus photographs and were assessed for the incidence, stage, and evolution of DR using modified Airlie House classification. Results. Among the 462 patients, 281 had no DR at baseline. The 5-year cumulative incidence of any DR was 10% (95% CI: 6–13), and only baseline microalbuminuria correlated with the development of DR (OR=10.53, 95% CI: 4.39–25.23, p<0.0001). Among the 181 patients with baseline DR, the worsening and regression rates of DR were 31.5% (95% CI: 25–38) and 9% (95% CI: 5–13), respectively. Microalbuminuria also approached statistical significance as a risk factor for DR worsening (OR=1.89, 95% CI: 0.97–3.70, p=0.06). Conclusion. The 5-year incidence of DR in this hospital-based cohort is relatively low. Microalbuminuria was independently associated with the incidence and progression of the disease. We recommend to screen patients with type II diabetes for microalbuminuria as prognostic for the development and worsening of DR. |
| format | Article |
| id | doaj-art-9c34b38009cd4fd996c08ff0bb85598a |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-9c34b38009cd4fd996c08ff0bb85598a2025-02-03T05:45:31ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/98051459805145Five-Year Incidence and Progression of Diabetic Retinopathy in Patients with Type II Diabetes in a Tertiary Care Center in LebanonCarl-Joe Mehanna0Maamoun Abdul Fattah1Hani Tamim2Mona P. Nasrallah3Raya Zreik4Sandra S. Haddad5Jaafar El-Annan6Randa S. Haddad7Haytham I. S. Salti8Department of Ophthalmology, American University of Beirut Medical Center, Beirut, LebanonDepartment of Ophthalmology, American University of Beirut Medical Center, Beirut, LebanonBiostatistics Unit, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonDivision of Endocrinology and Metabolism, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonDivision of Endocrinology and Metabolism, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, LebanonFouad Khoury Hospital Bikhazi Medical Group, Beirut, LebanonDepartment of Ophthalmology, University of Texas Medical Branch, Galveston, TX, USADepartment of Ophthalmology, American University of Beirut Medical Center, Beirut, LebanonDepartment of Ophthalmology, American University of Beirut Medical Center, Beirut, LebanonObjective. To estimate the 5-year incidence of progression rate and regression rate and risk factors for diabetic retinopathy (DR) in a cohort of Lebanese patients with type II diabetes. Methods. We followed a cohort of 462 Lebanese patients with type II diabetes for over 5 years at the American University of Beirut Medical Center. Patients underwent yearly complete ophthalmic evaluation and fundus photographs and were assessed for the incidence, stage, and evolution of DR using modified Airlie House classification. Results. Among the 462 patients, 281 had no DR at baseline. The 5-year cumulative incidence of any DR was 10% (95% CI: 6–13), and only baseline microalbuminuria correlated with the development of DR (OR=10.53, 95% CI: 4.39–25.23, p<0.0001). Among the 181 patients with baseline DR, the worsening and regression rates of DR were 31.5% (95% CI: 25–38) and 9% (95% CI: 5–13), respectively. Microalbuminuria also approached statistical significance as a risk factor for DR worsening (OR=1.89, 95% CI: 0.97–3.70, p=0.06). Conclusion. The 5-year incidence of DR in this hospital-based cohort is relatively low. Microalbuminuria was independently associated with the incidence and progression of the disease. We recommend to screen patients with type II diabetes for microalbuminuria as prognostic for the development and worsening of DR.http://dx.doi.org/10.1155/2017/9805145 |
| spellingShingle | Carl-Joe Mehanna Maamoun Abdul Fattah Hani Tamim Mona P. Nasrallah Raya Zreik Sandra S. Haddad Jaafar El-Annan Randa S. Haddad Haytham I. S. Salti Five-Year Incidence and Progression of Diabetic Retinopathy in Patients with Type II Diabetes in a Tertiary Care Center in Lebanon Journal of Ophthalmology |
| title | Five-Year Incidence and Progression of Diabetic Retinopathy in Patients with Type II Diabetes in a Tertiary Care Center in Lebanon |
| title_full | Five-Year Incidence and Progression of Diabetic Retinopathy in Patients with Type II Diabetes in a Tertiary Care Center in Lebanon |
| title_fullStr | Five-Year Incidence and Progression of Diabetic Retinopathy in Patients with Type II Diabetes in a Tertiary Care Center in Lebanon |
| title_full_unstemmed | Five-Year Incidence and Progression of Diabetic Retinopathy in Patients with Type II Diabetes in a Tertiary Care Center in Lebanon |
| title_short | Five-Year Incidence and Progression of Diabetic Retinopathy in Patients with Type II Diabetes in a Tertiary Care Center in Lebanon |
| title_sort | five year incidence and progression of diabetic retinopathy in patients with type ii diabetes in a tertiary care center in lebanon |
| url | http://dx.doi.org/10.1155/2017/9805145 |
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