Viral subversion of host cell Ca²⁺ signaling through STIM1-Orai1-mediated SOCE: Mechanisms and implications

Viral infection hijacks host cell physiological processes to replicate and spread, in which the calcium ion (Ca2 +) signaling pathway plays a key role in the viral life cycle. Store-operated Ca2+ entry (SOCE), as the major Ca²⁺ influx pathway, is regulated by the endoplasmic reticulum (ER) Ca2+ rece...

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Bibliographic Details
Main Authors: Qingqing Lu, Yuan Ding, Yan Zhang, Shuzhen Liu
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Pharmacological Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825002713
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