Pulmonary Embolism in the Elderly: From Symptoms to Speckle Tracking Echocardiography

(1) Background: There are little data about the differences in clinical and echocardiographic characteristics between elderly (aged ≥ 65 years) and younger patients with acute pulmonary embolism (PE). (2) Methods: Consecutive patients diagnosed with PE in a tertiary hospital were identified. Clinica...

Full description

Saved in:
Bibliographic Details
Main Authors: Christos Ballas, Dimitrios Sfairopoulos, Ioanna Samara, Lampros Lakkas, Olga Kardakari, Athanasios Konstantinidis, Katerina K. Naka, Lampros K. Michalis, Christos S. Katsouras
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/12/1/15
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832588291503816704
author Christos Ballas
Dimitrios Sfairopoulos
Ioanna Samara
Lampros Lakkas
Olga Kardakari
Athanasios Konstantinidis
Katerina K. Naka
Lampros K. Michalis
Christos S. Katsouras
author_facet Christos Ballas
Dimitrios Sfairopoulos
Ioanna Samara
Lampros Lakkas
Olga Kardakari
Athanasios Konstantinidis
Katerina K. Naka
Lampros K. Michalis
Christos S. Katsouras
author_sort Christos Ballas
collection DOAJ
description (1) Background: There are little data about the differences in clinical and echocardiographic characteristics between elderly (aged ≥ 65 years) and younger patients with acute pulmonary embolism (PE). (2) Methods: Consecutive patients diagnosed with PE in a tertiary hospital were identified. Clinical characteristics, biomarkers and transthoracic echocardiography indices including right ventricular free wall longitudinal strain (RV-FWLS) were recorded. (3) Results: Of 200 patients enrolled, 19 patients had high-risk PE and were excluded from the study. Compared to younger patients, elderly patients with PE had less frequently pain and typical symptoms and more often were hospitalized due to another reason before the PE diagnosis. The elderly had higher values of D-dimer, high-sensitivity troponin I and brain natriuretic peptide (BNP). Echocardiographic differences were noted and the elderly had lower values of pulmonary vascular acceleration time, RV E/A ratio and lower tricuspid annular plane systolic excursion/pulmonary artery systolic pressure ratio. The RV-FWLS index did not show a statistically significant difference in distribution between age groups ≥ 65 and <65 years old. The RV diameter was similar across all age groups. (4) Conclusions: The elderly have differences compared with younger patients with PE regarding the mode of presentation, the values of biomarkers like D-dimer, BNP and troponins and some echocardiographic indices of RV affection.
format Article
id doaj-art-9c106badf4e84a15bef349395a97ee2f
institution Kabale University
issn 2308-3425
language English
publishDate 2024-12-01
publisher MDPI AG
record_format Article
series Journal of Cardiovascular Development and Disease
spelling doaj-art-9c106badf4e84a15bef349395a97ee2f2025-01-24T13:35:59ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252024-12-011211510.3390/jcdd12010015Pulmonary Embolism in the Elderly: From Symptoms to Speckle Tracking EchocardiographyChristos Ballas0Dimitrios Sfairopoulos1Ioanna Samara2Lampros Lakkas3Olga Kardakari4Athanasios Konstantinidis5Katerina K. Naka6Lampros K. Michalis7Christos S. Katsouras8Department of Cardiac Surgery, University Hospital of Ioannina, 455 00 Ioannina, GreeceFirst Department of Cardiology, University Hospital of Ioannina, 455 00 Ioannina, GreeceService de Cardiologie, Hôpitaux du Pays du Mont Blanc, 747 00 Sallanches, FranceDepartment of Physiology, Faculty of Medicine, University of Ioannina, 451 10 Ioannina, GreeceSecond Department of Cardiology, University Hospital of Ioannina, 455 00 Ioannina, GreeceRespiratory Department, University Hospital of Ioannina, Respiratory Medicine, 455 00 Ioannina, GreeceSecond Department of Cardiology, University Hospital of Ioannina, 455 00 Ioannina, GreeceSecond Department of Cardiology, University Hospital of Ioannina, 455 00 Ioannina, GreeceFirst Department of Cardiology, University Hospital of Ioannina, 455 00 Ioannina, Greece(1) Background: There are little data about the differences in clinical and echocardiographic characteristics between elderly (aged ≥ 65 years) and younger patients with acute pulmonary embolism (PE). (2) Methods: Consecutive patients diagnosed with PE in a tertiary hospital were identified. Clinical characteristics, biomarkers and transthoracic echocardiography indices including right ventricular free wall longitudinal strain (RV-FWLS) were recorded. (3) Results: Of 200 patients enrolled, 19 patients had high-risk PE and were excluded from the study. Compared to younger patients, elderly patients with PE had less frequently pain and typical symptoms and more often were hospitalized due to another reason before the PE diagnosis. The elderly had higher values of D-dimer, high-sensitivity troponin I and brain natriuretic peptide (BNP). Echocardiographic differences were noted and the elderly had lower values of pulmonary vascular acceleration time, RV E/A ratio and lower tricuspid annular plane systolic excursion/pulmonary artery systolic pressure ratio. The RV-FWLS index did not show a statistically significant difference in distribution between age groups ≥ 65 and <65 years old. The RV diameter was similar across all age groups. (4) Conclusions: The elderly have differences compared with younger patients with PE regarding the mode of presentation, the values of biomarkers like D-dimer, BNP and troponins and some echocardiographic indices of RV affection.https://www.mdpi.com/2308-3425/12/1/15pulmonary embolismelderlyechocardiography
spellingShingle Christos Ballas
Dimitrios Sfairopoulos
Ioanna Samara
Lampros Lakkas
Olga Kardakari
Athanasios Konstantinidis
Katerina K. Naka
Lampros K. Michalis
Christos S. Katsouras
Pulmonary Embolism in the Elderly: From Symptoms to Speckle Tracking Echocardiography
Journal of Cardiovascular Development and Disease
pulmonary embolism
elderly
echocardiography
title Pulmonary Embolism in the Elderly: From Symptoms to Speckle Tracking Echocardiography
title_full Pulmonary Embolism in the Elderly: From Symptoms to Speckle Tracking Echocardiography
title_fullStr Pulmonary Embolism in the Elderly: From Symptoms to Speckle Tracking Echocardiography
title_full_unstemmed Pulmonary Embolism in the Elderly: From Symptoms to Speckle Tracking Echocardiography
title_short Pulmonary Embolism in the Elderly: From Symptoms to Speckle Tracking Echocardiography
title_sort pulmonary embolism in the elderly from symptoms to speckle tracking echocardiography
topic pulmonary embolism
elderly
echocardiography
url https://www.mdpi.com/2308-3425/12/1/15
work_keys_str_mv AT christosballas pulmonaryembolismintheelderlyfromsymptomstospeckletrackingechocardiography
AT dimitriossfairopoulos pulmonaryembolismintheelderlyfromsymptomstospeckletrackingechocardiography
AT ioannasamara pulmonaryembolismintheelderlyfromsymptomstospeckletrackingechocardiography
AT lamproslakkas pulmonaryembolismintheelderlyfromsymptomstospeckletrackingechocardiography
AT olgakardakari pulmonaryembolismintheelderlyfromsymptomstospeckletrackingechocardiography
AT athanasioskonstantinidis pulmonaryembolismintheelderlyfromsymptomstospeckletrackingechocardiography
AT katerinaknaka pulmonaryembolismintheelderlyfromsymptomstospeckletrackingechocardiography
AT lamproskmichalis pulmonaryembolismintheelderlyfromsymptomstospeckletrackingechocardiography
AT christosskatsouras pulmonaryembolismintheelderlyfromsymptomstospeckletrackingechocardiography