Targeting the chemokine receptor CXCR4 for cancer therapies

Abstract The C-X-C chemokine receptor type 4 (CXCR4) has emerged as a key molecular biomarker for cancer therapies due to its critical role in tumor progression and metastases by displaying a stem cells phenotype. Its overexpression has been observed in more than 20 types of cancers, including solid...

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Bibliographic Details
Main Authors: Ariana Rueda, Naroa Serna, Ramon Mangues, Antonio Villaverde, Ugutz Unzueta
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Biomarker Research
Subjects:
Online Access:https://doi.org/10.1186/s40364-025-00778-y
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