Use of hydrophilic pharmaceutical excipients to modulate release of metal ions from silicone elastomers

Use of hydrophilic pharmaceutical excipients to modulate release of metal ions from silicone elastomers

Silicone elastomers based on polydimethylsiloxane are biocompatible and non-biodegradable thermosetting polymers used in various drug delivery applications, including subdermal implants, vaginal rings, and intrauterine devices. Without exception, all marketed silicone elastomer drug delivery product...

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Bibliographic Details
Main Authors: Xin Shen, Xinyu Zhao, Clare F. McCoy, Yahya H. Dallal Bashi, Peter Boyd, R. Karl Malcolm
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Drug Delivery
Subjects:
Drug delivery
gelatin
polyvinylpyrrolidone
hydroxypropyl methylcellulose
sucrose
silicone rubber
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2025.2545515
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