Protective factors against oxidative stress in COPD: focus on Nrf2-dependent antioxidant gene expression

Chronic obstructive pulmonary disease (COPD) continues to be the world’s primary cause of morbidity and mortality. The main mechanism driving the pathogenesis of COPD is oxidative stress. Antioxidant genes, regulated by the Nrf2/ARE signaling pathway, play a protective role against oxidative stress....

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Bibliographic Details
Main Authors: Eva Kominkova, Martin Petrek, Zdenka Navratilova
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1492256/full
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