Unwanted disorders and xenogeneic graft‐versus‐host disease in experimental immunodeficient mice: How to evaluate and how to report
Abstract Human‐derived tumor models are essential for preclinical development of new anticancer drug entities. Generating animal models bearing tumors of human origin, such as patient‐derived or cell line–derived xenograft tumors, is dependent on immunodeficient strains. Tumor‐bearing immunodeficien...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2025-01-01
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Series: | Animal Models and Experimental Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/ame2.12509 |
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