Exposure to “Forever Chemical” perfluorooctanoic acid induces depression-like behaviors in mice by activating the HPA axis

Perfluorooctanoic acid (PFOA), an environmental endocrine disruptor, has been found to increase the expression of corticotropin-releasing factor (CRF) in the paraventricular nucleus (PVN). In this study, adult male mice were given PFOA by oral gavage (p.o.) to evaluate whether it disrupts systems re...

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Bibliographic Details
Main Authors: Ya Wang, Yuning Chen, Houlin Chen, James N Samsom, Minfei Shu, Xuehui Gao, Qiyu Li, Kangmin Chen, Le Wang, Fang Liu
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Environment International
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Online Access:http://www.sciencedirect.com/science/article/pii/S0160412025003824
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