Methylcobalamin-containing nanofiber sheets have better neuroprotective effects than small intestinal submucosa sheets

Methylcobalamin-containing nanofiber sheets have better neuroprotective effects than small intestinal submucosa sheets

Abstract Postoperative adhesion around nerves sometimes results in sensory and motor dysfunctions. To prevent these disorders, we have developed an electrospun nanofiber sheet incorporating methylcobalamin (MeCbl), an active form of vitamin B12 with anti-inflammatory and neuroregenerative effects. T...

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Main Authors: Yoshiaki Yoshimura, Toru Iwahashi, Taisuke Kasuya, Toshiki Shimada, Katsuyuki Konishi, Atsushi Kamata, Mai Konishi, Arisa Kazui, Ryoya Shiode, Satoshi Miyamura, Kunihiro Oka, Seiji Okada, Hiroyuki Tanaka
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-78933-y
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https://doi.org/10.1038/s41598-024-78933-y

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