Dual orexin receptor antagonists as promising therapeutics for Alzheimer’s disease
Abstract We examine the relationship between sleep, glymphatics and Alzheimer’s disease (AD), and recent work questioning glymphatic clearance during sleep. We highlight a need for understanding glymphatic and/or other mechanism of clearance during sleep, and review glymphatic flow measurement metho...
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| Main Authors: | S. M. Ragsdale, J. M. Radovich, I. I. Coiduras, W. V. McCall, S. C. Grant, C. Lee, A. Wilber |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
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| Series: | npj Biological Timing and Sleep |
| Online Access: | https://doi.org/10.1038/s44323-025-00025-5 |
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