Rare Homozygous CTSC Deletion in Siblings with Papillon-Lefevre Syndrome: A Case Report

Papillon-Lefevre syndrome (PLS) is an extremely rare autosomal recessive genodermatosis caused by mutations in the cathepsin C (CTSC) gene. It is characterized by palmoplantar keratoderma (PPK), periodontopathy, intracranial calcifications, and recurrent pyogenic infections. We encountered an Emirat...

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Bibliographic Details
Main Authors: Fatima AlQaydi, Mohamed Ahmed
Format: Article
Language:English
Published: QAASPA Publisher 2025-06-01
Series:BioMed Target Journal
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Online Access:https://qaaspa.com/index.php/bmtj/article/view/86
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