Elevated serum IL-10/IL-6 ratio as a novel biomarker for secondary central nervous system lymphoma and poor prognosis in DLBCL

Elevated serum IL-10/IL-6 ratio as a novel biomarker for secondary central nervous system lymphoma and poor prognosis in DLBCL

IntroductionDiffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma and carries a poor prognosis when it involves the central nervous system (CNS), a condition known as secondary CNS lymphoma (SCNSL). Although the CNS International Prognostic Index (CNS-IPI) is used...

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Bibliographic Details
Main Authors: Jingjing Wen, Xingyu Nie, Qiaolin Zhou, Yiping Liu, Jing Yue, Ya Zhang, Jing Su, Xiaogong Liang, Fang Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
diffuse large B-cell lymphoma
central nervous system
interleukin-10
interleukin-6
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1656044/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1656044/full

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