Proteomic surveys of the mouse heart unveil cardiovascular responses to nitric oxide/cGMP signaling deficiencies

Proteomic surveys of the mouse heart unveil cardiovascular responses to nitric oxide/cGMP signaling deficiencies

Abstract Diminished bioavailability of nitric oxide (NO) contributes to the pathogenesis of cardiometabolic disorders. However, the alterations in signaling under NO deficiency remain mostly unknown. We combined genetics and proteomics to quantify changes in the heart proteome, phosphoproteome, and...

Full description

Saved in:
Bibliographic Details
Main Authors: Ipsita Mohanty, Hossein Fazelinia, Serena Raimo, Hua Ding, Lynn Spruce, Maria Symeonidou, Margarita Tenopoulou, Fumito Ichinose, Hirotaka Yamashita, Hiroaki Shimokawa, Tsutsui Masato, Paschalis-Thomas Doulias, Harry Ischiropoulos
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08203-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s42003-025-08203-8

Similar Items