Real-world effectiveness of mepolizumab in Japanese asthma patients with diverse backgrounds: Improvements in rhinosinusitis imaging (J-Real-Mepo)

Real-world effectiveness of mepolizumab in Japanese asthma patients with diverse backgrounds: Improvements in rhinosinusitis imaging (J-Real-Mepo)

Background: Although randomized controlled trials (RCT) have demonstrated the efficacy of mepolizumab for asthma, they have excluded certain patient subgroups. To bridge the gap between RCT and real-world practice, the effectiveness of mepolizumab in a diverse population, including those potentially...

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Main Authors: Hiroyuki Nagase, Konomi Kobayashi, Makiko Toma-Hirano, Maho Suzukawa, Norihiro Harada, Katsunori Masaki, Yoshito Miyata, Mayoko Tsuji, Junko Terada-Hirashima, Keiko Komatsuzaki, Hitoshi Sasano, Kenji Mizumura, Ryoji Kagoya, Yuya Shimizu, Shintaro Yoshihara, Norio Kihara, Yasunari Miyazaki, Toshiyuki Koya, Naruhiko Sugihara, Nobuhisa Ishikawa, Masayuki Hojo, Etsuko Tagaya, Akihiko Tanaka, Koichi Fukunaga, Yasuhiro Gon
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Allergology International
Subjects:
Eosinophilic asthma
Eosinophilic chronic rhinosinusitis
Exclusion criteria
Lund–Mackay score
Real-world
Online Access:http://www.sciencedirect.com/science/article/pii/S132389302400162X
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