The ACE2/Apelin Signaling, MicroRNAs, and Hypertension

The renin-angiotensin aldosterone system (RAAS) plays a pivotal role in the development of hypertension. Angiotensin converting enzyme 2 (ACE2), which primarily metabolises angiotensin (Ang) II to generate the beneficial heptapeptide Ang-(1-7), serves as a negative regulator of the RAAS. Apelin is a...

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Bibliographic Details
Main Authors: Lai-Jiang Chen, Ran Xu, Hui-Min Yu, Qing Chang, Jiu-Chang Zhong
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2015/896861
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