Development and Validation of UPLC-MS/MS Method for Determination of Enasidenib in Rat Plasma and Its Pharmacokinetic Application
In our research, a straightforward UPLC-MS/MS method, with diazepam as the internal standard (IS), was proposed and acknowledged to determine the concentrations of enasidenib in rat plasma. When preparing the sample, we used acetonitrile for protein precipitation. The gradient elution method was use...
Saved in:
Main Authors: | Shuang-long Li, Yong-liang Zhu, Yi Zhang, Shu-han Liu, Xiang-die Wang, Xiang-jun Qiu |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2020-01-01
|
Series: | International Journal of Analytical Chemistry |
Online Access: | http://dx.doi.org/10.1155/2020/5084127 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Determination of Tropifexor in Beagle Dog Plasma by UPLC-MS/MS and Its Application in Pharmacokinetics
by: Yan-Ding Su, et al.
Published: (2022-01-01) -
Validated UPLC-MS/MS Method for Determination of Futibatinib and Its Pharmacokinetics in Beagle Dogs
by: Heng Li, et al.
Published: (2022-01-01) -
Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach
by: Pei Liu, et al.
Published: (2022-01-01) -
Rapid, Validated UPLC-MS/MS Method for Determination of Glibenclamide in Rat Plasma
by: Mohd Aftab Alam, et al.
Published: (2018-01-01) -
Determination of Tenacissoside G, Tenacissoside H, and Tenacissoside I in Rat Plasma by UPLC-MS/MS and Their Pharmacokinetics
by: Fan Chen, et al.
Published: (2023-01-01)