Development and Validation of UPLC-MS/MS Method for Determination of Enasidenib in Rat Plasma and Its Pharmacokinetic Application

In our research, a straightforward UPLC-MS/MS method, with diazepam as the internal standard (IS), was proposed and acknowledged to determine the concentrations of enasidenib in rat plasma. When preparing the sample, we used acetonitrile for protein precipitation. The gradient elution method was use...

Full description

Saved in:
Bibliographic Details
Main Authors: Shuang-long Li, Yong-liang Zhu, Yi Zhang, Shu-han Liu, Xiang-die Wang, Xiang-jun Qiu
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2020/5084127
Tags: Add Tag
No Tags, Be the first to tag this record!