Interventions to Reduce Serum Per- and Poly-Fluoroalkyl Substances Levels, Improve Cardiovascular Risk Profiles, and Improve Epigenetic Age Acceleration in US Firefighters: Protocol for Randomized Controlled Trial

BackgroundOccupational cancer and acute cardiac events are the leading causes of death among firefighters. Increased exposure to toxicants on the fire ground, such as polycyclic aromatic hydrocarbons, benzene, and per- and poly-fluoroalkyl substances (PFAS), has been linked t...

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Main Authors: Reagan Conner, Cynthia Porter, Karen Lutrick, Shawn C Beitel, James Hollister, Olivia Healy, Krystal J Kern, Floris Wardenaar, John J Gulotta, Kepra Jack, Matthew Huentelman, Jefferey L Burgess, Melissa Furlong
Format: Article
Language:English
Published: JMIR Publications 2025-04-01
Series:JMIR Research Protocols
Online Access:https://www.researchprotocols.org/2025/1/e67120
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