Association of SUDOSCAN Values with Vibration Perception Threshold in Chinese Patients with Type 2 Diabetes Mellitus
Aims/Introduction. SUDOSCAN has been proved to be an efficient method in detecting diabetic microvascular complications. In this study, we determine to detect the possible relationship between vibration perception threshold (VPT) and cardiac autonomic neuropathy (CAN) values produced by SUDOSCAN. Ma...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2017/8435252 |
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| author | Xiaoming Zhu Fei Mao Siying Liu Hangping Zheng Bin Lu Yiming Li |
| author_facet | Xiaoming Zhu Fei Mao Siying Liu Hangping Zheng Bin Lu Yiming Li |
| author_sort | Xiaoming Zhu |
| collection | DOAJ |
| description | Aims/Introduction. SUDOSCAN has been proved to be an efficient method in detecting diabetic microvascular complications. In this study, we determine to detect the possible relationship between vibration perception threshold (VPT) and cardiac autonomic neuropathy (CAN) values produced by SUDOSCAN. Materials and Methods. A total of 920 Chinese patients with T2DM were enrolled in the study. Spearman correlation analysis and multivariate regression analysis were performed to determine the relation between CAN and VPT values. Mean VPT values across the CAN value tertiles were analyzed stratified by HbA1c status. Results. In the study, we discovered a relatively high correlation between CAN value and both VPT values from dorsal feet and toes. Multivariate regression analyses also showed a significant relation between VPT and CAN values after adjusting all covariates. The mean value of VPT decreased across the SUDOSCAN-CAN value quartiles in both groups, and it was higher in patients with HbA1C > 9% than in patients with HbA1C < 9% across all quartiles of the SUDOSCAN-CAN except for the VPT mean in the low quartile of the SUDOSCAN-CAN value. Conclusions. All these results suggested that SUDOSCAN-CAN result was associated with VPT value which indicated a probable link between VPT value and cardiovascular autonomic dysfunction. |
| format | Article |
| id | doaj-art-9a4992e0bbf14f67bec27f395fccbfc3 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-9a4992e0bbf14f67bec27f395fccbfc32025-02-03T01:31:57ZengWileyInternational Journal of Endocrinology1687-83371687-83452017-01-01201710.1155/2017/84352528435252Association of SUDOSCAN Values with Vibration Perception Threshold in Chinese Patients with Type 2 Diabetes MellitusXiaoming Zhu0Fei Mao1Siying Liu2Hangping Zheng3Bin Lu4Yiming Li5Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, ChinaAims/Introduction. SUDOSCAN has been proved to be an efficient method in detecting diabetic microvascular complications. In this study, we determine to detect the possible relationship between vibration perception threshold (VPT) and cardiac autonomic neuropathy (CAN) values produced by SUDOSCAN. Materials and Methods. A total of 920 Chinese patients with T2DM were enrolled in the study. Spearman correlation analysis and multivariate regression analysis were performed to determine the relation between CAN and VPT values. Mean VPT values across the CAN value tertiles were analyzed stratified by HbA1c status. Results. In the study, we discovered a relatively high correlation between CAN value and both VPT values from dorsal feet and toes. Multivariate regression analyses also showed a significant relation between VPT and CAN values after adjusting all covariates. The mean value of VPT decreased across the SUDOSCAN-CAN value quartiles in both groups, and it was higher in patients with HbA1C > 9% than in patients with HbA1C < 9% across all quartiles of the SUDOSCAN-CAN except for the VPT mean in the low quartile of the SUDOSCAN-CAN value. Conclusions. All these results suggested that SUDOSCAN-CAN result was associated with VPT value which indicated a probable link between VPT value and cardiovascular autonomic dysfunction.http://dx.doi.org/10.1155/2017/8435252 |
| spellingShingle | Xiaoming Zhu Fei Mao Siying Liu Hangping Zheng Bin Lu Yiming Li Association of SUDOSCAN Values with Vibration Perception Threshold in Chinese Patients with Type 2 Diabetes Mellitus International Journal of Endocrinology |
| title | Association of SUDOSCAN Values with Vibration Perception Threshold in Chinese Patients with Type 2 Diabetes Mellitus |
| title_full | Association of SUDOSCAN Values with Vibration Perception Threshold in Chinese Patients with Type 2 Diabetes Mellitus |
| title_fullStr | Association of SUDOSCAN Values with Vibration Perception Threshold in Chinese Patients with Type 2 Diabetes Mellitus |
| title_full_unstemmed | Association of SUDOSCAN Values with Vibration Perception Threshold in Chinese Patients with Type 2 Diabetes Mellitus |
| title_short | Association of SUDOSCAN Values with Vibration Perception Threshold in Chinese Patients with Type 2 Diabetes Mellitus |
| title_sort | association of sudoscan values with vibration perception threshold in chinese patients with type 2 diabetes mellitus |
| url | http://dx.doi.org/10.1155/2017/8435252 |
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