Digital PCR-based genetic profiling from vitreous fluid as liquid biopsy for primary uveal melanoma: a proof-of-concept study

Abstract Background Uveal melanoma is an aggressive ocular malignancy. Early molecular characterisation of primary tumours is crucial to identify those at risk of metastatic dissemination. Although tumour biopsies are being taken, liquid biopsies of ocular fluids may form a less invasive but relativ...

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Main Authors: R. J. Nell, M. Versluis, N. V. Menger, M. C. Gelmi, T. H.K. Vu, R. M. Verdijk, G. P.M. Luyten, M. J. Jager, P. A. van der Velden
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:https://doi.org/10.1186/s13046-025-03374-y
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