Dynamic changes in peripheral blood lymphocyte trajectory predict the clinical outcomes of sepsis

BackgroundSepsis induces profound derangements in the immune system, including lymphopenia, which correlates with immunosuppression and poor prognosis. However, most evaluations of immunosuppression in sepsis patients rely on static, sporadic lymphocyte counts, lacking dynamic modeling over the dise...

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Bibliographic Details
Main Authors: Dongkai Li, Jiahui Zhang, Wei Cheng, Guoyu Zhao, Xianli Lei, Yawen Xie, Na Cui, Hao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1431066/full
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