Bisphenol A attenuates testosterone synthesis via increasing apolipoprotein A1-mediated reverse cholesterol transport in mice

Bisphenol A attenuates testosterone synthesis via increasing apolipoprotein A1-mediated reverse cholesterol transport in mice

Bisphenol A (BPA), a widely used chemical compound in plastic manufacturing, has become ubiquitous in the environment. Previous studies have highlighted its adverse effects on reproductive function, as BPA exposure reduces testosterone levels. Cholesterol is involved in testosterone synthesis in Ley...

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Bibliographic Details
Main Authors: Tong Zhao, Wenzhe Yang, Feilong Pan, Jinhao Wang, Wenqi Shao, Fangfang Chen, Kexiang Liu, Shuchen Zhao, Lijia Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Endocrinology
Subjects:
bisphenol A
apolipoprotein A1
cholesterol
reverse cholesterol transport
testosterone
lipid droplet
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1514105/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1514105/full

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