Targeting olfactory receptor OR2AT4: An innovative aptamer-based treatment for hair growth promotion

Targeting olfactory receptor OR2AT4: An innovative aptamer-based treatment for hair growth promotion

Non-canonical functions of olfactory receptors, one of the largest families of GPCR receptors not confined to the olfactory system, include an intriguing role on hair physiology. Previous studies using odorant agonists of the Olfactory Receptor family 2 subfamily AT member 4 (OR2AT4) showed hair gro...

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Main Authors: Manuel Mataix, Nuria Illera, Inés Hidalgo, Maria del Carmen de Arriba, Elena Martín, Gerónimo Fernández, Carlos González, Fernando Larcher, Victor M. González, Marcela del Rio, Francisco Jiménez, Marta Carretero
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Oligonucleotides: Therapies and Applications
alopecia
olfactory receptor
OR2AT4
aptamer
antimicrobial peptides
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253125001623
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