Biological effect of tissue plasminogen activator (t-PA) and DNase intrapleural delivery in pleural infection patients

Background Pleural infection (PI) is a major global disease with an increasing incidence, and pleural fluid (PF) drainage is essential for the successful treatment. The MIST2 study demonstrated that intrapleural administration of tissue plasminogen activator (t-PA) and DNase, or t-PA alone increased...

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Bibliographic Details
Main Authors: Najib M Rahman, Rob Hallifax, Ioannis Psallidas, Melissa Dobson, John M Wrightson, Nikolaos I Kanellakis, Eihab O Bedawi, Rachel Mercer, Maged Hassan, Rachelle Asciak, Emma Hedley, Tao Dong
Format: Article
Language:English
Published: BMJ Publishing Group 2019-10-01
Series:BMJ Open Respiratory Research
Online Access:https://bmjopenrespres.bmj.com/content/6/1/e000440.full
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