Distinct characteristics of BTLA/HVEM axis expression on Tregs and its impact on the expansion and attributes of Tregs in patients with active pulmonary tuberculosis

Distinct characteristics of BTLA/HVEM axis expression on Tregs and its impact on the expansion and attributes of Tregs in patients with active pulmonary tuberculosis

IntroductionPulmonary tuberculosis (PTB) remains one of the deadliest infectious diseases. Understanding PTB immunity is of potential value for exploring immunotherapy for treating chemotherapy-resistant PTB. CD4+CD25+Foxp3+ regulatory T cells (Tregs) are key players that impair immune responses to...

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Bibliographic Details
Main Authors: Peijun Tang, Xinghua Shen, Jianling Gao, Jianping Zhang, Yanjun Feng, Ji Zhang, Ziyi Huang, Xuefeng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
pulmonary tuberculosis
Tregs
BTLA
HVEM
PD-L1
PD-1
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1437207/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2024.1437207/full

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