Polygenic risk score for acute rejection based on donor-recipient non-HLA genotype mismatch.

Polygenic risk score for acute rejection based on donor-recipient non-HLA genotype mismatch.

<h4>Background</h4>Acute rejection (AR) after kidney transplantation is an important allograft complication. To reduce the risk of post-transplant AR, determination of kidney transplant donor-recipient mismatching focuses on blood type and human leukocyte antigens (HLA), while it remains...

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Main Authors: Rui Cao, David P Schladt, Casey Dorr, Arthur J Matas, William S Oetting, Pamala A Jacobson, Ajay Israni, Jinbo Chen, Weihua Guan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0303446
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https://doi.org/10.1371/journal.pone.0303446

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