Renal Response Criteria for Clinical Trials in Amyloid Light Chain Amyloidosis

Renal Response Criteria for Clinical Trials in Amyloid Light Chain Amyloidosis

Immunoglobin light chain (AL) amyloidosis is a rare disease characterized by organ deposition of amyloid fibrils, most commonly in the heart and kidney. Disease heterogeneity necessitates organ-specific assessment to determine prognosis and response or progression. To facilitate development of new t...

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Bibliographic Details
Main Authors: Nelson Leung, Raymond Comenzo, Julian Gillmore, Andrea Havasi, Efstathios Kastritis, Spencer Guthrie, James Signorovitch, Dena Heath, Isabelle Lousada, Yolanda Barbachano, Krishna Prasad, Kimberly Smith
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Kidney International Reports
Subjects:
AL amyloidosis
clinical trial
estimated glomerular filtration rate
proteinuria
renal end points
rare diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024924016206
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