The role of TRECs/KRECs as immune indicators that reflect immunophenotypes and predict the risk of infection in systemic autoimmune diseases

The role of TRECs/KRECs as immune indicators that reflect immunophenotypes and predict the risk of infection in systemic autoimmune diseases

T cell receptor rearrangement excision circles (TRECs) and immunoglobulin κ-deleting recombination excision circles (KRECs) represent the lymphopoiesis capacity, widely used for newborn screening of inborn errors of immunity. To clarify the significance of TRECs and KRECs as immune indicators in pat...

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Main Authors: Takuji Itakura, Hirokazu Sasaki, Tadashi Hosoya, Natsuka Umezawa, Tetsuya Saito, Hideyuki Iwai, Hisanori Hasegawa, Hiroyuki Sato, Akihiro Hirakawa, Kohsuke Imai, Tomohiro Morio, Naoki Kimura, Shinsuke Yasuda
Format: Article
Language:English
Published: Taylor & Francis Group 2025-02-01
Series:Immunological Medicine
Subjects:
T cells
B cells
immunosuppressants
TRECs
KRECs
Online Access:https://www.tandfonline.com/doi/10.1080/25785826.2025.2460275
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https://www.tandfonline.com/doi/10.1080/25785826.2025.2460275

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