Exosome Loaded in Microneedle Patch Ameliorates Renal Ischemia–Reperfusion Injury in a Mouse Model
Conclusion: The use of a microneedle patch containing exosomes is a noninvasive method that enables the release of exosomes in a slow manner. In comparison to exosome injection alone, microneedle patch-exosome treatment offers a longer and more targeted effect that improves renal IRI dysfunction and...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/sci/3106634 |
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| _version_ | 1832591047223410688 |
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| author | Samin Taghavi Somayeh Keshtkar Mozhgan Abedanzadeh Mehrdad Hashemi Reza Heidari Samira Sadat Abolmaali Mahintaj Dara Mahdokht Hossein Aghdaei Alireza Sabegh Negar Azarpira |
| author_facet | Samin Taghavi Somayeh Keshtkar Mozhgan Abedanzadeh Mehrdad Hashemi Reza Heidari Samira Sadat Abolmaali Mahintaj Dara Mahdokht Hossein Aghdaei Alireza Sabegh Negar Azarpira |
| author_sort | Samin Taghavi |
| collection | DOAJ |
| description | Conclusion: The use of a microneedle patch containing exosomes is a noninvasive method that enables the release of exosomes in a slow manner. In comparison to exosome injection alone, microneedle patch-exosome treatment offers a longer and more targeted effect that improves renal IRI dysfunction and reduces tissue damage, potentially facilitating the clinical application of exosomes and improving graft survival. |
| format | Article |
| id | doaj-art-98cd512a91124ce4a3fd43d9691c6bea |
| institution | Kabale University |
| issn | 1687-9678 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-98cd512a91124ce4a3fd43d9691c6bea2025-01-23T05:00:03ZengWileyStem Cells International1687-96782025-01-01202510.1155/sci/3106634Exosome Loaded in Microneedle Patch Ameliorates Renal Ischemia–Reperfusion Injury in a Mouse ModelSamin Taghavi0Somayeh Keshtkar1Mozhgan Abedanzadeh2Mehrdad Hashemi3Reza Heidari4Samira Sadat Abolmaali5Mahintaj Dara6Mahdokht Hossein Aghdaei7Alireza Sabegh8Negar Azarpira9Transplant Research CenterMolecular Dermatology Research CenterPharmaceutical Nanotechnology Department and Center for Nanotechnology in Drug DeliveryDepartment of GeneticsPharmaceutical Sciences Research CenterPharmaceutical Nanotechnology Department and Center for Nanotechnology in Drug DeliveryStem Cells Technology Research CenterTransplant Research CenterTransplant Research CenterTransplant Research CenterConclusion: The use of a microneedle patch containing exosomes is a noninvasive method that enables the release of exosomes in a slow manner. In comparison to exosome injection alone, microneedle patch-exosome treatment offers a longer and more targeted effect that improves renal IRI dysfunction and reduces tissue damage, potentially facilitating the clinical application of exosomes and improving graft survival.http://dx.doi.org/10.1155/sci/3106634 |
| spellingShingle | Samin Taghavi Somayeh Keshtkar Mozhgan Abedanzadeh Mehrdad Hashemi Reza Heidari Samira Sadat Abolmaali Mahintaj Dara Mahdokht Hossein Aghdaei Alireza Sabegh Negar Azarpira Exosome Loaded in Microneedle Patch Ameliorates Renal Ischemia–Reperfusion Injury in a Mouse Model Stem Cells International |
| title | Exosome Loaded in Microneedle Patch Ameliorates Renal Ischemia–Reperfusion Injury in a Mouse Model |
| title_full | Exosome Loaded in Microneedle Patch Ameliorates Renal Ischemia–Reperfusion Injury in a Mouse Model |
| title_fullStr | Exosome Loaded in Microneedle Patch Ameliorates Renal Ischemia–Reperfusion Injury in a Mouse Model |
| title_full_unstemmed | Exosome Loaded in Microneedle Patch Ameliorates Renal Ischemia–Reperfusion Injury in a Mouse Model |
| title_short | Exosome Loaded in Microneedle Patch Ameliorates Renal Ischemia–Reperfusion Injury in a Mouse Model |
| title_sort | exosome loaded in microneedle patch ameliorates renal ischemia reperfusion injury in a mouse model |
| url | http://dx.doi.org/10.1155/sci/3106634 |
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