Canonical correlation analysis for multi-omics: Application to cross-cohort analysis.

Canonical correlation analysis for multi-omics: Application to cross-cohort analysis.

Integrative approaches that simultaneously model multi-omics data have gained increasing popularity because they provide holistic system biology views of multiple or all components in a biological system of interest. Canonical correlation analysis (CCA) is a correlation-based integrative method desi...

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Main Authors: Min-Zhi Jiang, François Aguet, Kristin Ardlie, Jiawen Chen, Elaine Cornell, Dan Cruz, Peter Durda, Stacey B Gabriel, Robert E Gerszten, Xiuqing Guo, Craig W Johnson, Silva Kasela, Leslie A Lange, Tuuli Lappalainen, Yongmei Liu, Alex P Reiner, Josh Smith, Tamar Sofer, Kent D Taylor, Russell P Tracy, David J VanDenBerg, James G Wilson, Stephen S Rich, Jerome I Rotter, Michael I Love, Laura M Raffield, Yun Li, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Analysis Working Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-05-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010517&type=printable
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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010517&type=printable

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