Feasibility, safety and tolerability of estrogen and/or probiotics for improving vaginal health in Canadian African, Caribbean, and Black women: A pilot phase 1 clinical trial.

Feasibility, safety and tolerability of estrogen and/or probiotics for improving vaginal health in Canadian African, Caribbean, and Black women: A pilot phase 1 clinical trial.

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<h4>Background</h4>A dysbiotic vaginal microbiome (VMB) is associated with clinical conditions such as bacterial vaginosis (BV) and an increased risk of human immunodeficiency virus (HIV-1) infection. Considering the high prevalence of BV among African, Caribbean and Black (ACB) women, w...

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Main Authors: Biban Gill, Jocelyn M Wessels, Christina L Hayes, Jenna Ratcliffe, Junic Wokuri, Elizabeth Ball, Gregor Reid, Rupert Kaul, Jesleen Rana, Muna Alkhaifi, Wangari Tharao, Fiona Smaill, Charu Kaushic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0315576
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https://doi.org/10.1371/journal.pone.0315576

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