On a mathematical model of bone marrow metastatic niche
We propose a mathematical model to describe tumor cells movement towards a metastasis location into the bone marrow considering the influence of chemotaxis inhibition due to the action of a drug. The model considers the evolution of the signaling molecules CXCL-12 secreted by osteoblasts (bone cells...
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Main Authors: | Ana Isabel Muñoz, J. Ignacio Tello |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2016-12-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2017019 |
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