On a mathematical model of bone marrow metastatic niche

We propose a mathematical model to describe tumor cells movement towards a metastasis location into the bone marrow considering the influence of chemotaxis inhibition due to the action of a drug. The model considers the evolution of the signaling molecules CXCL-12 secreted by osteoblasts (bone cells...

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Bibliographic Details
Main Authors: Ana Isabel Muñoz, J. Ignacio Tello
Format: Article
Language:English
Published: AIMS Press 2016-12-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2017019
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