Investigating the Epigenetic Landscape of Major Depressive Disorder: A Genome-Wide Meta-Analysis of DNA Methylation Data, Including New Insights into Stochastic Epigenetic Mutations and Epivariations

Investigating the Epigenetic Landscape of Major Depressive Disorder: A Genome-Wide Meta-Analysis of DNA Methylation Data, Including New Insights into Stochastic Epigenetic Mutations and Epivariations

<b>Background/Objectives:</b> Major depressive disorder (MDD) is a mental health condition that can severely impact patients’ social lives, leading to withdrawal and difficulty in maintaining relationships. Environmental factors such as trauma and stress can worsen MDD by interacting wit...

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Bibliographic Details
Main Authors: Giulia Nicole Baldrighi, Rebecca Cavagnola, Luciano Calzari, Davide Sacco, Lucy Costantino, Fulvio Ferrara, Davide Gentilini
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Biomedicines
Subjects:
MDD
epigenetic drift
rare epivariations
epigenetics
Online Access:https://www.mdpi.com/2227-9059/12/10/2181
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