Age- and Sex-Specific Gut Microbiota Signatures Associated with Dementia-Related Brain Pathologies: An LEfSe-Based Metagenomic Study

Age- and Sex-Specific Gut Microbiota Signatures Associated with Dementia-Related Brain Pathologies: An LEfSe-Based Metagenomic Study

Background/Objectives: Emerging evidence suggests that gut microbiota composition is influenced by both age and sex and may contribute to dementia-related brain pathologies. However, comprehensive microbiome-based biomarker discovery stratified by these factors remains limited. Methods: We performed...

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Bibliographic Details
Main Authors: Sun Hwa Hong, Hyun Woong Roh, You Jin Nam, Tae Wi Kim, Yong Hyuk Cho, Sang Joon Son, Chang Hyung Hong
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Brain Sciences
Subjects:
gut microbiota
dementia-related brain pathologies
sex-specific differences
age-related characteristics
metagenomic analysis
biomarkers
Online Access:https://www.mdpi.com/2076-3425/15/6/611
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