NHCs Catalyzed Hydrophosphonylation of α-Ketoesters and α-Trifluoromethyl Ketones

N-Heterocyclic carbenes catalyzed hydrophosphonylation reaction of α-ketoesters and α-trifluoromethyl ketones was developed. Under the catalysis of 10 mol% IPr, α-ketoesters or α-trifluoromethyl ketones reacted with dialkyl phosphites to provide quaternary α-hydroxyphosphonates in good to excellent...

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Bibliographic Details
Main Authors: Lin He, Zhi-Hua Cai, Ji-Xin Pian, Guang-Fen Du
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2013/890187
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