Effect of Tiaoxin Recipe on Memory Learning and Synaptic Plasticity in APP/PS1 Double Transgenic Alzheimer's Disease Mice based on αCaMKⅡ-CREB-BDNF Signal Pathway

Effect of Tiaoxin Recipe on Memory Learning and Synaptic Plasticity in APP/PS1 Double Transgenic Alzheimer's Disease Mice based on αCaMKⅡ-CREB-BDNF Signal Pathway

Objective:To observe the effects of Tiaoxin recipe on long-term potentiation (LTP) in hippocampal CA1 region, hippocampal alpha calcium/calmodulin-dependent kinaseⅡ (αCaMKⅡ), cyclic adenosine monophosphate response element binding protein (CREB), brain derived neurotrophic factor (BDNF), postsynapti...

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Bibliographic Details
Main Authors: Xiaowen WANG, Hong QIAN, Chunjuan SHEN, Yanjun LI, Haixin YUAN, Jian WANG
Format: Article
Language:English
Published: Editorial Office of Rehabilitation Medicine 2020-08-01
Series:康复学报
Subjects:
Alzheimer's disease
Tiaoxin recipe
synaptic plasticity
learning and memory
alpha calcium/calmodulin-dependent protein kinaseⅡ
cyclic adenosine monophosphate response element binding protein
brain-derived neurotrophic factor
signaling pathway
Online Access:http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2020.04010
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http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2020.04010

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