Nonfamilial, MPL S505N-Mutated Essential Thrombocythaemia

Mutations of MPL are present in a significant proportion of patients with the myeloproliferative neoplasms (MPN), primary myelofibrosis (PMF), and essential thrombocythaemia (ET). The most frequent of these mutations, W515L and W515K, occur in exon 10 of MPL, which encodes the receptor for thrombopo...

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Bibliographic Details
Main Authors: Ruth Morrell, Stephen E. Langabeer, Liam Smyth, Meegahage Perera, Gerard Crotty
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2013/729327
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