When the heart deceives: a case report of hyperthyroidism disguised as STEMI in female pregnant patient

Abstract Background Acute myocardial infarction during pregnancy is a rare condition with an incidence of 1 to 10 per 100,000 deliveries. ST-elevation myocardial infarction (STEMI) is dominating the clinical presentation. It is estimated that 29% of the patients had normal coronary arteries, and hyp...

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Main Authors: Kevin Wibawa, Lidia Debby Wiyono, Raditya Dewangga, Arief Sumarna, Wizhar Syamsuri, Yandi Ariffudin, Suhendiwijaya Suhendiwijaya, Pangeran Akbar Syah
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:The Egyptian Heart Journal
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Online Access:https://doi.org/10.1186/s43044-025-00607-5
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author Kevin Wibawa
Lidia Debby Wiyono
Raditya Dewangga
Arief Sumarna
Wizhar Syamsuri
Yandi Ariffudin
Suhendiwijaya Suhendiwijaya
Pangeran Akbar Syah
author_facet Kevin Wibawa
Lidia Debby Wiyono
Raditya Dewangga
Arief Sumarna
Wizhar Syamsuri
Yandi Ariffudin
Suhendiwijaya Suhendiwijaya
Pangeran Akbar Syah
author_sort Kevin Wibawa
collection DOAJ
description Abstract Background Acute myocardial infarction during pregnancy is a rare condition with an incidence of 1 to 10 per 100,000 deliveries. ST-elevation myocardial infarction (STEMI) is dominating the clinical presentation. It is estimated that 29% of the patients had normal coronary arteries, and hyperthyroidism may be associated with coronary vasospasm. Case Presentation: A 30-year-old pregnant woman was referred with inferior STEMI post-failed fibrinolytic therapy. Her hospitalization course was complicated by non-sustained ventricular tachycardia and cardiogenic shock. Coronary angiography revealed normal coronary arteries without intracoronary thrombus, coronary dissection, or coronary atherosclerotic lesion. Laboratory test showed high Free T4 2.71 ng/dL and low TSH < 0.05 mlU/mL. Patient’s condition and hospitalization course were significantly improved after the initiation of hyperthyroid therapy. We suspected a hyperthyroid-induced coronary vasospasm as a potential etiology of myocardial infarction with non-obstructive coronary artery (MINOCA) in this patient. Conclusion Although MINOCA due to hyperthyroidism is a rare finding among pregnant young woman, recognizing this etiology is a paramount of importance due to improved survival with appropriate and specific therapy.
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institution Kabale University
issn 2090-911X
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publishDate 2025-01-01
publisher SpringerOpen
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series The Egyptian Heart Journal
spelling doaj-art-982695c9595b4a4da738a8c7f7a99b592025-01-19T12:28:22ZengSpringerOpenThe Egyptian Heart Journal2090-911X2025-01-017711510.1186/s43044-025-00607-5When the heart deceives: a case report of hyperthyroidism disguised as STEMI in female pregnant patientKevin Wibawa0Lidia Debby Wiyono1Raditya Dewangga2Arief Sumarna3Wizhar Syamsuri4Yandi Ariffudin5Suhendiwijaya Suhendiwijaya6Pangeran Akbar Syah7Department of Cardiology and Vascular Medicine, Rumah Sakit Umum Daerah Gunung JatiDepartment of Internal Medicine, Rumah Sakit Umum Daerah Gunung JatiDepartment of Cardiology and Vascular Medicine, Rumah Sakit Umum Daerah Gunung JatiDepartment of Internal Medicine, Rumah Sakit Umum Daerah Gunung JatiDepartment of Internal Medicine, Rumah Sakit Umum Daerah Gunung JatiDepartment of Cardiology and Vascular Medicine, Rumah Sakit Umum Daerah Gunung JatiDepartment of Cardiology and Vascular Medicine, Rumah Sakit Umum Daerah Gunung JatiDepartment of Cardiology and Vascular Medicine, Rumah Sakit Umum Daerah Gunung JatiAbstract Background Acute myocardial infarction during pregnancy is a rare condition with an incidence of 1 to 10 per 100,000 deliveries. ST-elevation myocardial infarction (STEMI) is dominating the clinical presentation. It is estimated that 29% of the patients had normal coronary arteries, and hyperthyroidism may be associated with coronary vasospasm. Case Presentation: A 30-year-old pregnant woman was referred with inferior STEMI post-failed fibrinolytic therapy. Her hospitalization course was complicated by non-sustained ventricular tachycardia and cardiogenic shock. Coronary angiography revealed normal coronary arteries without intracoronary thrombus, coronary dissection, or coronary atherosclerotic lesion. Laboratory test showed high Free T4 2.71 ng/dL and low TSH < 0.05 mlU/mL. Patient’s condition and hospitalization course were significantly improved after the initiation of hyperthyroid therapy. We suspected a hyperthyroid-induced coronary vasospasm as a potential etiology of myocardial infarction with non-obstructive coronary artery (MINOCA) in this patient. Conclusion Although MINOCA due to hyperthyroidism is a rare finding among pregnant young woman, recognizing this etiology is a paramount of importance due to improved survival with appropriate and specific therapy.https://doi.org/10.1186/s43044-025-00607-5Acute myocardial infarctionHyperthyroidismPregnancySTEMI
spellingShingle Kevin Wibawa
Lidia Debby Wiyono
Raditya Dewangga
Arief Sumarna
Wizhar Syamsuri
Yandi Ariffudin
Suhendiwijaya Suhendiwijaya
Pangeran Akbar Syah
When the heart deceives: a case report of hyperthyroidism disguised as STEMI in female pregnant patient
The Egyptian Heart Journal
Acute myocardial infarction
Hyperthyroidism
Pregnancy
STEMI
title When the heart deceives: a case report of hyperthyroidism disguised as STEMI in female pregnant patient
title_full When the heart deceives: a case report of hyperthyroidism disguised as STEMI in female pregnant patient
title_fullStr When the heart deceives: a case report of hyperthyroidism disguised as STEMI in female pregnant patient
title_full_unstemmed When the heart deceives: a case report of hyperthyroidism disguised as STEMI in female pregnant patient
title_short When the heart deceives: a case report of hyperthyroidism disguised as STEMI in female pregnant patient
title_sort when the heart deceives a case report of hyperthyroidism disguised as stemi in female pregnant patient
topic Acute myocardial infarction
Hyperthyroidism
Pregnancy
STEMI
url https://doi.org/10.1186/s43044-025-00607-5
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