Effect of liver biopsy size on MASLD fibrosis assessment by second-harmonic generation/two-photon excitation fluorescence microscopy

Effect of liver biopsy size on MASLD fibrosis assessment by second-harmonic generation/two-photon excitation fluorescence microscopy

Background & Aims: Fibrosis in metabolic dysfunction-associated steatotic liver disease (MASLD) is a prognostic indicator and clinical trial efficacy endpoint. Second-harmonic generation/two-photon excitation fluorescence (SHG/TPEF) microscopy images unstained tissue sections and, when integ...

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Bibliographic Details
Main Authors: Daniel T. Field, Yayun Ren, Kutbuddin Akbary, Elaine Chng, Dean Tai, Nikolai V. Naoumov, David E. Kleiner, Jonathan A. Fallowfield, Timothy J. Kendall, Arun J. Sanyal
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:JHEP Reports
Subjects:
Humans
Metabolic dysfunction-associated steatotic liver disease
Non-alcoholic fatty liver disease
Liver cirrhosis
Biopsy
Artificial intelligence
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555925001272
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