Spinal Cord Stimulation Alleviates Sensitization of Neuropathic Pain by Upregulating G Protein-Coupled Receptors to Inhibit Overexpression of Cav2.2 and Its Downstream Excitatory Neurotransmitters

Spinal Cord Stimulation Alleviates Sensitization of Neuropathic Pain by Upregulating G Protein-Coupled Receptors to Inhibit Overexpression of Cav2.2 and Its Downstream Excitatory Neurotransmitters

Si-Liang Liu,1,2 Hong-En Zhang,2,3 Ji-Yu Kang,2,3 Huai-Yu Ji,3 Zhen-Hua Cai,4 Si-Hua Qi,1 Shan-Shan Liu,3 Hua-Cheng Zhou2,3 1Department of Anesthesiology, the Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, People’s Republic of China; 2NHC Key Laboratory of Mol...

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Bibliographic Details
Main Authors: Liu SL, Zhang HE, Kang JY, Ji HY, Cai ZH, Qi SH, Liu SS, Zhou HC
Format: Article
Language:English
Published: Dove Medical Press 2025-06-01
Series:Journal of Pain Research
Subjects:
Neuropathic pain
Pain sensitization
Spinal cord stimulation
N-type calcium channels
Glutamate
Substance P
Online Access:https://www.dovepress.com/spinal-cord-stimulation-alleviates-sensitization-of-neuropathic-pain-b-peer-reviewed-fulltext-article-JPR
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