Protective role of 3-mercaptopyruvate sulfurtransferase (MPST) in the development of metabolic syndrome and vascular inflammation

Protective role of 3-mercaptopyruvate sulfurtransferase (MPST) in the development of metabolic syndrome and vascular inflammation

Metabolic syndrome (MetS) is a cluster of metabolic abnormalities that occur concurrently and increase the risk of cardiovascular disease. 3-mercaptopyruvate sulfurtransferase (MPST) is a cysteine-catabolizing enzyme that yields pyruvate and hydrogen sulfide (H2S) and plays a central role in the reg...

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Bibliographic Details
Main Authors: Paraskevas Zampas, Zhen Li, Antonia Katsouda, Aimilia Varela, Stelios Psarras, Constantinos H. Davos, David J. Lefer, Andreas Papapetropoulos
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Pharmacological Research
Subjects:
Metabolic syndrome
Hydrogen sulfide
Hypertension
Diastolic dysfunction
Vascular inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661824004870
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