A survey of sequence-to-graph mapping algorithms in the pangenome era

A survey of sequence-to-graph mapping algorithms in the pangenome era

Abstract A pangenome can reveal the genetic diversity across different individuals simultaneously. It offers a more comprehensive reference for genome analysis compared to a single linear genome that may introduce allele bias. Pangenomes are often represented as genome graphs, making sequence-to-gra...

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Bibliographic Details
Main Authors: Yingbo Cui, Chenchen Peng, Zeyu Xia, Canqun Yang, Yifei Guo
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Genome Biology
Subjects:
Pangenome
Sequence-to-graph Mapping
Seed-and-extend
Online Access:https://doi.org/10.1186/s13059-025-03606-6
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