Severe Acute Pulmonary Toxicity Associated with Brentuximab in a Patient with Refractory Hodgkin’s Lymphoma
Acute pulmonary toxicity associated with brentuximab appears to be a rare but serious adverse effect that can be potentially fatal. We report the case of a twenty-nine-year-old female with Hodgkin’s lymphoma who was treated with brentuximab and later presented with severe acute pulmonary toxicity; s...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Pulmonology |
| Online Access: | http://dx.doi.org/10.1155/2016/2359437 |
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| author | Yasmin Sabet Saul Ramirez Elizabeth Rosell Cespedes Marimer Rensoli Velasquez Mateo Porres-Muñoz Sumit Gaur Juan B. Figueroa-Casas Mateo Porres-Aguilar |
| author_facet | Yasmin Sabet Saul Ramirez Elizabeth Rosell Cespedes Marimer Rensoli Velasquez Mateo Porres-Muñoz Sumit Gaur Juan B. Figueroa-Casas Mateo Porres-Aguilar |
| author_sort | Yasmin Sabet |
| collection | DOAJ |
| description | Acute pulmonary toxicity associated with brentuximab appears to be a rare but serious adverse effect that can be potentially fatal. We report the case of a twenty-nine-year-old female with Hodgkin’s lymphoma who was treated with brentuximab and later presented with severe acute pulmonary toxicity; she improved after the discontinuation of brentuximab and administration of antibiotics and glucocorticoid therapy. Currently there is very little data in the literature in regard to the clinical manifestations and characteristics of patients taking brentuximab and the potential development of acute severe pulmonary toxicity, as well as the appropriate therapeutic approach, making this particular case of successful treatment and resolution unique. |
| format | Article |
| id | doaj-art-97597dc83eae4b5c94e5b6973b5d5814 |
| institution | Kabale University |
| issn | 2090-6846 2090-6854 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pulmonology |
| spelling | doaj-art-97597dc83eae4b5c94e5b6973b5d58142025-02-03T01:31:26ZengWileyCase Reports in Pulmonology2090-68462090-68542016-01-01201610.1155/2016/23594372359437Severe Acute Pulmonary Toxicity Associated with Brentuximab in a Patient with Refractory Hodgkin’s LymphomaYasmin Sabet0Saul Ramirez1Elizabeth Rosell Cespedes2Marimer Rensoli Velasquez3Mateo Porres-Muñoz4Sumit Gaur5Juan B. Figueroa-Casas6Mateo Porres-Aguilar7Division of General Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USADivision of Medical Education, Paul L. Foster School of Medicine and Texas Tech University HSC, El Paso, TX 79905, USADivision of General Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USADivision of General Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USASchool of Medicine, Universidad Autonoma de Tamaulipas (UAT), Tampico, MexicoDivision of Hematology and Oncology, Texas Tech University Health Sciences Center, El Paso, TX 79905, USADivision of Pulmonary and Critical Care Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USADivision of General Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USAAcute pulmonary toxicity associated with brentuximab appears to be a rare but serious adverse effect that can be potentially fatal. We report the case of a twenty-nine-year-old female with Hodgkin’s lymphoma who was treated with brentuximab and later presented with severe acute pulmonary toxicity; she improved after the discontinuation of brentuximab and administration of antibiotics and glucocorticoid therapy. Currently there is very little data in the literature in regard to the clinical manifestations and characteristics of patients taking brentuximab and the potential development of acute severe pulmonary toxicity, as well as the appropriate therapeutic approach, making this particular case of successful treatment and resolution unique.http://dx.doi.org/10.1155/2016/2359437 |
| spellingShingle | Yasmin Sabet Saul Ramirez Elizabeth Rosell Cespedes Marimer Rensoli Velasquez Mateo Porres-Muñoz Sumit Gaur Juan B. Figueroa-Casas Mateo Porres-Aguilar Severe Acute Pulmonary Toxicity Associated with Brentuximab in a Patient with Refractory Hodgkin’s Lymphoma Case Reports in Pulmonology |
| title | Severe Acute Pulmonary Toxicity Associated with Brentuximab in a Patient with Refractory Hodgkin’s Lymphoma |
| title_full | Severe Acute Pulmonary Toxicity Associated with Brentuximab in a Patient with Refractory Hodgkin’s Lymphoma |
| title_fullStr | Severe Acute Pulmonary Toxicity Associated with Brentuximab in a Patient with Refractory Hodgkin’s Lymphoma |
| title_full_unstemmed | Severe Acute Pulmonary Toxicity Associated with Brentuximab in a Patient with Refractory Hodgkin’s Lymphoma |
| title_short | Severe Acute Pulmonary Toxicity Associated with Brentuximab in a Patient with Refractory Hodgkin’s Lymphoma |
| title_sort | severe acute pulmonary toxicity associated with brentuximab in a patient with refractory hodgkin s lymphoma |
| url | http://dx.doi.org/10.1155/2016/2359437 |
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