Human umbilical cord mesenchymal stem cell-derived exosomes enhance follicular regeneration in androgenetic alopecia via activation of Wnt/β-catenin pathway

Human umbilical cord mesenchymal stem cell-derived exosomes enhance follicular regeneration in androgenetic alopecia via activation of Wnt/β-catenin pathway

Abstract Background Exosomes isolated from human umbilical cord mesenchymal stem cells (hUCMSCs) have demonstrated the capacity to alleviate dihydrotestosterone (DHT)-induced disruptions in the hair follicle growth cycle. However, the precise role and underlying mechanisms by which hUCMSC-derived ex...

Full description

Saved in:
Bibliographic Details
Main Authors: Aiqing Yu, Yujun Zhang, Saifeng Zhong, Zhizhen Yang, Mingming Xie
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Stem Cell Research & Therapy
Subjects:
HUCMSCs derived-exosomes
Hair follicle growth cycle
Androgenetic alopecia
Dihydrotestosterone
Human dermal papilla cells
Online Access:https://doi.org/10.1186/s13287-025-04538-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s13287-025-04538-5

Similar Items