Hydration with Mannitol and Dextrose May Promote Cisplatin-Induced Nephrotoxicity: Test of Five Protocols of Hydration during Cisplatin Therapy in Rat Models

Backgrounds. Cisplatin (CP) still is a novel choice for solid tumor therapy, but it is accompanied with the side effect of nephrotoxicity. Hydration may reduce the risk of CP-induced nephrotoxicity, while the issue is still challenging. In this study, five types of hydration protocols including sali...

Full description

Saved in:
Bibliographic Details
Main Authors: Mohammad-Sedigh Khosravi, Alireza Samimiat, Bahar Mazaheri, Farzaneh Ashrafi, Ardeshir Talebi, Mehdi Nematbakhsh
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2021/5547341
Tags: Add Tag
No Tags, Be the first to tag this record!