Divalent Metal- and High Mobility Group N Protein-Dependent Nucleosome Stability and Conformation

High mobility group N proteins (HMGNs) bind specifically to the nucleosome core and act as chromatin unfolding and activating factors. Using an all-Xenopus system, we found that HMGN1 and HMGN2 binding to nucleosomes results in distinct ion-dependent conformation and stability. HMGN2 association wit...

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Bibliographic Details
Main Authors: Michelle S. Ong, Dileep Vasudevan, Curt A. Davey
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.4061/2010/143890
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