Sperm miR‐142‐3p Reprogramming Mediates Paternal Pre‐Pregnancy Caffeine Exposure‐Induced Non‐Alcoholic Steatohepatitis in Male Offspring Rats

Sperm miR‐142‐3p Reprogramming Mediates Paternal Pre‐Pregnancy Caffeine Exposure‐Induced Non‐Alcoholic Steatohepatitis in Male Offspring Rats

Abstract Numerous studies have suggested a strong association between paternal adverse environmental exposure and increased disease susceptibility in offspring. However, the impact of paternal pre‐pregnant caffeine exposure (PPCE) on offspring health remains unexplored. This study elucidates the spe...

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Bibliographic Details
Main Authors: Cong Zhang, Yu Guo, Yi Liu, Kexin Liu, Wen Hu, Hui Wang
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Advanced Science
Subjects:
ACSL4
miR‐142‐3p
non‐alcoholic steatohepatitis
paternal pre‐pregnant caffeine exposure
sperm reprogramming
Online Access:https://doi.org/10.1002/advs.202405592
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https://doi.org/10.1002/advs.202405592

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