SIRT7 affects the proliferation and apoptosis of papillary thyroid cancer cells by desuccinylation of LATS1

Abstract Background Papillary thyroid cancer (PTC) is one of the malignant tumors with rapidly increasing morbidity and mortality. Sirtuin 7 (SIRT7) is a desuccinylase that is involved in tumorigenesis. The activation of large tumor suppressor 1 (LATS1) can effectively suppress tumorigenesis in mult...

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Bibliographic Details
Main Authors: Qinghua Li, Gang Pu
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-025-13779-9
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